CURRICULUM VITAE

Bertelli

Luiz Bertelli, PhD

Los Alamos National Laboratory
Internal Dosimetry
RP-2, Health Physics Measurements
Mailstop G761
Los Alamos, NM 87545
Phone: work:(505) 664-0292
E-mail: lbertelli@lanl.gov

Dr. Bertelli received his MS in Nuclear Engineering from the Military Institute of Engineering in Brazil and his PhD in Biophysics from the Federal University of Rio de Janeiro. He later did a postdoctoral fellowship at the University of Utah in the United States. At the time of the Goiânia incident, he was a Research Scientist at the IRD/CNEN. In the late-80's he was a Senior Research Scientist for the Institute of Radiation Protection & Dosimetry (IRD) at the Brazilian National Nuclear Energy Commission (CNEN). He is now an Internal Dosimetrist at Los Alamos National Laboratory (LANL).

Summary of Qualifications

a) Mathematical modeling of human metabolism regarding intake, distribution, retention and excretion of radionuclides for several age groups.
b) Simulations of radiation transport through human organs and tissues using the Monte Carlo technique, applicable to environmental, occupational and medical cases of internal and external exposure to ionizing radiation.
c) Statistical analysis, reliability of models, dose assessment.
d) Human and animal data interpretation and validation
e) Evaluation of the efficiency of the administration of chelating (decontaminating) agents to internally contaminated people with emphasis to DTPA and Prussian Blue.
f) Prospective and retrospective dose assessments. Evaluation of intakes of radionuclides and estimates of internal and external doses.
g) Regulatory compliance of workplaces with radioactive materials.
h) Analysis of litigation cases involving human exposure to ionizing radiation.
i) Scientific software design and development including software quality assurance procedures.
j) Design, analysis, construction and maintenance of databases.
k) Development, improvement and maintenance of dose assessment systems dealing with massive amounts of data (thousands of workers and measurements in a single year)
l) Specialist in internal dosimetry for actinides.
m) Professor in postgraduate courses and academic advisor of Ph.D. and M.Sc. theses.

Main projects, products and tasks associated with ICRP activities:

Member of the Task Group on Dose Calculations of the International Commission on Radiological Protection (ICRP), since September 1995.

AIDE: Internal Dosimetry Software (Radiat Prot Dosimetry, July 2008; 130: 358 – 367). This software,or its calculation core, is one of those used in quality assurance procedures of the ICRP internal dose coefficients since 1996. It was also used to generate the tables of activities in compartments and dose coefficients of the NCRP Report No. 156, Development of a Biokinetic Model for Radionuclide-Contaminated Wounds and Procedures for Their Assessment, Dosimetry and Treatment

CD-ROM: ICRP Doses to the Embryo and Fetus from Intakes of Radionuclides by the Mother. As a member of the Task Group on Dose Calculations of the International Commission on Radiological Protection (K.F. Eckerman, R.W. Leggett, V. Berkovski, I.A. Likhtarev, L. Bertelli, D. Nosske, A.W. Phipps and G.M. Kendall), distributed by Elsevier Science Ltd, New York, USA 2001-2002.

CD-ROM: ICRP Database of Dose Coefficients: Workers and Members of the Public

As a member of the Task Group on Dose Calculations of the International Commission on Radiological Protection (K.F. Eckerman, R.W. Leggett, V. Berkovski, I.A. Likhtarev, L. Bertelli, D. Nosske, A.W. Phipps and G.M. Kendall), distributed by Elsevier Science Ltd, New York, USA 1997 – 2001 (http://www.elsevier.com/inca/publications/store/6/2/2/6/1/1/index.htt)

Sponsored by Lovelace Respiratory Research Institute, Albuquerque, New Mexico: Analysis of the Sensitivity of the International Commission on Radiological Protection (ICRP) Publication No. 66 Respiratory Tract Dosimetry Model, With Respect to Various Model Parameters and Radionuclides 1998 - 1999

Sponsored by Brazilian National Council for Scientific and Technological Development (CNPq): Grant on Productivity in Research: A Respiratory Tract Model Modified to Simulate Inhalation of Uranium Compounds Applied to Interpretations of Bioassay Measurements (305425/88-9 NV) 1995 - 1999

Sponsored by Atomic Energy Control Board of Canada: Evaluation of Data and Models on Uranium Metabolism (North America) (AECB Project # 3.111.2) 1991 - 1994

Sponsored by Brazilian National Council for Scientific and Technological Development (CNPq): Postdoctoral Fellowship (201656/90-6) 1991 - 1993

Sponsored by International Atomic Energy Agency: Medical Aspects of the Goiania Accident (BRA 9/034) Metabolic modeling for the several age groups, bioassay data interpretation, dose calculations and preliminary evaluation of the efficiency of the administration of chelating (decontaminating) agents to the Goiania victims. 1989 - 1990.

Sponsored by German/Brazilian Cooperation Program: Incorporation Monitoring 1986 - 1990.

Experience:
Scientific and Technical:

  • Mathematical modeling (design, algorithm construction, coding and testing):
    1. Computerized mathematical simulations of the human metabolism, applicable in predictive modeling and in reconstructing situations of medical, environmental, accidental and occupational intakes of radioactive and non-radioactive materials for several age groups. Simulations of human intake of radioactive materials through inhalation, ingestion and injection of radionuclides, deposition in the several body organs and tissues and excretion through feces and urine through analytical solutions of systems of first order linear differential equations.
    2. Human data interpretation (direct radiation measurements in body organs and in urinary and fecal excretions) using biokinetic models, for reconstructing cases of intakes of radionuclides.
    3. Human and animal biological data fitting to biokinetic models in order to obtain and validate compound specific parameters for metabolic simulations of intake, retention and excretion of radionuclides.
    4. Statistical analysis of human and animal data.
    5. Analysis of sensitivity and reliability of models.
    6. Quality assurance procedures for technical/scientific software.
    7. Computerized mathematical simulations and validations through comparison with measurements of radiation transport through human organs and tissues and calculation of radiation doses, applicable to medical and environmental cases of exposure to ionizing radiation for several age groups.
    8. Author and co-author of about one hundred scientific and technical papers in the field of radiological sciences.
  • Statistical analysis of human and animal data.
  • Analysis of sensitivity and reliability of models.
  • Quality assurance procedures for technical/scientific software.
  • Computerized mathematical simulations and validations through comparison with measurements of radiation transport through human organs and tissues and calculation of radiation doses, applicable to medical and environmental cases of exposure to ionizing radiation for several age groups.
  • Author and co-author of about one hundred scientific and technical papers in the field of radiological sciences.

Managerial:

  • Management of personnel and projects concerning internal individual monitoring as the head of a division, which was constituted of two laboratories and a metabolic modeling and dosimetry group.
  • Coordinator and professor of national (Brazilian) and international technical courses and workshops.

Teaching and Training:

  • Advisor of academic Ph.D. (attached list) and M.Sc. theses.
  • Professor in postgraduate courses (health physics, internal and external dosimetry) at the following Brazilian universities between 1995 and 1998: State University of Rio de Janeiro, Military Institute of Engineering, University of São Paulo in the city of Ribeirão Preto, Federal University of Pernambuco in the city of Recife.
  • Physics laboratory teacher for High School students at Colegio Santa Cruz, São Paulo, Brazil between 1973 and 1977.

Computer Applications and Programming:

  • Languages: FORTRAN, Visual Basic 6, database management and business solutions, SQL, Microsoft Development Tools, Windows 2000 and XP
  • Applications in Windows and DOS: word processors, spreadsheets and databases (Excel, Access), statistical analysis, technical graphing programs (Sigmaplot, Origin) and presentation software.

Education:

  • Doctor of Philosophy Degree, Biophysics, Federal University of Rio de Janeiro (1990). Thesis topic: Proposal for Optimization in the Interpretation of Bioassay Data for Workers Exposed to Internal Contamination, (in Portuguese). Courses in scientific methodology, statistics, stochastic processes, simulation, linear programming, radiobiology, cellular biophysics and radiation dosimetry.
  • Master of Science Degree, Nuclear Engineering, Military Institute of Engineering (1980). Thesis topic: Proposal of a Model for the Calculation of Doses and Risk due to Inhalation and Ingestion of Radionuclides from Nuclear Facilities (in Portuguese).
  • Bachelor of Science, Physics, University of São Paulo (1977).

Languages:

Language Reading Writing Speaking Understand
English Excel. Excel. Excel. Excel.
Spanish Excel. Reg. Excel. Excel.
German Good Reg. Reg. Reg.
Italian Excel. Poor Reg. Excel.
French Good --- Poor Reg.
Portuguese Mother Tongue

Citizenship: USA

Employment History:

  • Health Physicist (Internal Dosimetry) – Los Alamos National Laboratory, 10/2003 - present
  • Internal Dosimetry Specialist – Argonne National Laboratory, 05/2002 – 09/2003
  • Software Engineer at EDO Corp. (ceramic materials for telecommunications), 11/2000 – 04/2002
  • Consultant on radiation protection, 01/1999-present
  • Institute of Radiation Protection and Dosimetry (IRD), Brazilian National Nuclear Energy Commission (CNEN), Rio de Janeiro, Brazil; Senior Research Scientist, 06/1995-12/1998.
  • University of Utah; Postdoctoral Fellow and IRD/CNEN; Senior Research Scientist (on leave), 06/1991-05/1995.
  • IRD/CNEN; Senior Research Scientist and Head of Internal Monitoring Division, 05/1988-05/1991.
  • IRD/CNEN; Research Scientist, 12/1980-05/1988.
  • Colegio Santa Cruz, São Paulo, Brazil; High School Teacher, 03/1973 – 12/1977

Awards:

  • Young Scientist Award given by Radiation Protection Research Action of the Commission of the European Communities to participate in the "Workshop on Intakes of Radionuclides: Detection, Assessment and Limitation of Occupational Exposure", at Bath, U.K., 13-17 September 1993.
  • Young Scientist Award given by Radiation Protection Research Action of the Commission of the European Communities to participate in the "Workshop on Intakes of Radionuclides: Occupational and Public Exposure", at Avignon, France, 15-18 September 1997.
  • Pacesetter Award (quick response to special US-DOE inquiries in accident preparedness and terrorist attacks), Argonne National Laboratory, 2003
  • Two Spot Awards (for quickly meeting all software quality assurance requirements established by LANL applied to a computerized system for calculating internal doses of radiation workers), Los Alamos National Laboratory, 2005

Memberships:

Member of the ICRP Task Group on Dose Calculations (ICRP/DOCAL) since September 1996

Member of the European Radiation Dosimetry Group (EURADOS)

American Health Physics Society, Internacional Collaboration Committee since 2005

Member of the Editorial Board of "RADIOPROTECTION, Revue de la Société Française de Radioprotection" (Journal of the French Radiation Protection Society) since January 2011

Most Recent Publications (complete list upon request):

Three Plutonium Chelation Cases At Los Alamos National Laboratory
Bertelli, L.; Waters, T.L.; Miller, G.; Gadd, M.S.; Eaton, M.C.; Guilmette, R.A. Health Physics. 99(4):532-538, October 2010.

Poisson mixture model for measurements using counting
G. Miller, A. Justus, V. Vostrotin, D. Dry, and L. Bertelli Radiat Prot Dosimetry, 138(4): 363-375, 2010

Uncertainties in Internal Doses Calculated for Mayak Workers--A Study of 63 Cases
G. Miller, R. Guilmette, L. Bertelli, T. Waters, S. A. Romanov, and Y. V. Zaytseva Radiat Prot Dosimetry, Advance Access published on August 8, 2008; doi: doi:10.1093/rpd/ncn181

IMPDOS (Improved Dosimetry and Risk Assessment for Plutonium-Induced Diseases): Internal Dosimetry Software Tools Developed for the Mayak Worker Study
G. Miller, L. Bertelli, and R. Guilmette Radiat Prot Dosimetry, Advance Access published on July 25, 2008; doi: doi:10.1093/rpd/ncn178

AIDE: Internal Dosimetry Software
L. Bertelli, D. R. Melo, J. Lipsztein, and R. Cruz-Suarez Radiat Prot Dosimetry, July 2008; 130: 358 - 367.

A Study of Early Los Alamos Internal Exposures to Plutonium
G. Miller, L. Bertelli, R. Guilmette, M. W. McNaughton, and W. F. Eisele Radiat Prot Dosimetry, July 2008; 130: 503 - 509.

An Empirical Multivariate Log-Normal Distribution Representing Uncertainty of Biokinetic Parameters for 137Cs
G. Miller, D. Melo, H. Martz, and L. Bertelli Radiat Prot Dosimetry, Advance Access published on April 16, 2008; doi: doi:10.1093/rpd/ncn131

Technical Basis for Using Nose Swab Bioassay Data for Early Internal Dose Assessment
Raymond A. Guilmette, Luiz Bertelli, Guthrie Miller, and Tom T. Little Radiat Prot Dosimetry, November 2007; 127: 356 - 360.

Use of Air Monitoring and Experimental Aerosol Data for Intake Assessment for Mayak Plutonium Workers
Yekaterina V. Zaytseva, Fyodor D. Tretyakov, Sergey A. Romanov, Guthrie Miller, Luiz Bertelli, and Raymond A. Guilmette Radiat Prot Dosimetry, November 2007; 127: 535 - 539.

Internal Dose Assessment Data Management System for a Large Population of Pu Workers
L. Bertelli, G. Miller, T. Little, R. A. Guilmette, and S. M. Glasser Radiat Prot Dosimetry, November 2007; 127: 347 - 349.

Comparison of Dose Estimation from Occupational Exposure to 239Pu Using Different Modelling Approaches
S. A. Romanov, R. A. Guilmette, V. F. Khokhryakov, A. Phipps, E. E. Aladova, L. Bertelli, A. Birchall, K. F. Eckerman, V. V. Khokhryakov, M. P. Krahenbuhl, R. W. Leggett, T. T. Little, G. Miller, S. C. Miller, A. Riddell, K. G. Suslova, V. V. Vostrotin, and Ye. V. Zaytseva Radiat Prot Dosimetry, November 2007; 127: 486 - 490.

Internal Dosimetry Verification and Validation Database
G. Miller, L. Bertelli, T. Little, and R. A. Guilmette Radiat Prot Dosimetry, November 2007; 127: 361 - 369. The NCRP Wound Model: Development and Application Raymond A. Guilmette, Patricia W. Durbin, Richard E. Toohey, and Luiz Bertelli Radiat Prot Dosimetry, November 2007; 127: 103 - 107.

Uranium Dose Assessment: a Bayesian Approach to the Problem of Dietary Background
Tom Little, Guthrie Miller, Raymond Guilmette, and Luiz Bertelli Radiat Prot Dosimetry, November 2007; 127: 333 - 338.

Worldwide Bioassay Data Resources for Plutonium/americium Internal Dosimetry Studies
G. Miller, A. E. Riddell, R. Filipy, L. Bertelli, T. Little, and R. Guilmette Radiat Prot Dosimetry, July 2007; 125: 531 - 537