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Research Project Description

Lung Injury Treatment Development Fellowship
Immediate Office
Office of Clinical Pharmacology
Center for Drug Evaluation and Research
U.S. Food and Drug Administration
Silver Spring, MD

FDA-CDER-2013-0019

Project Description:

A fellowship opportunity is available in the Immediate Office within the Office of Clinical Pharmacology (OCP-IO) at the Center for Drug Evaluation and Research (CDER) of the U.S. Food and Drug Administration (FDA). OCP’s mission is aimed at assuring the safety and effectiveness of new drugs through evaluation of clinical pharmacology and biopharmaceutics data.

The selected participant will be involved in a variety of research activities related to identifying a potential treatment for chemical-induced lung injury through repurposing a combination of 3-4 FDA-approved drugs. Activities may include mining external credible gene expression, protein-protein interaction, and pathway databases, as well as knowledge bases to construct the disease network and the extended pharmacological networks of drugs that cause lung injury. S/he will utilize various computation and visualization software tools to carry out this research project.

The Research Participation Program for FDA is administered by the Oak Ridge Institute for Science and Education (ORISE). The initial appointment is for two years, but may be renewed upon recommendation of FDA contingent on the availability of funds. The participant will receive a monthly stipend depending on educational level and experience. The participant must show proof of health insurance. The appointment is full-time at FDA in the Silver Spring, Maryland, area. Participants do not become employees of FDA or the program administrator, and there are no fringe benefits paid.

Qualifications:

  • A Doctoral degree in bioinformatics, computational biology or systems biology received within the last five years. Ph.D. candidates are also encouraged to apply.
  • Experience in machine learning and analysis of gene expression data is desired.
  • Demonstrated experience with programming languages (i.e., XML, C, Java, Perl, or Matlab) is also desired.

How to Apply:

To be considered, please send a current CV/resume to the attention of FDArpp@orau.org. Please reference FDA-CDER-2013-0019 in all communications.