Research Project Description
Cell Death Regulation Postdoctoral Fellowship
Division of Therapeutic Proteins
Office of Biotechnology Products
Center for Drug Evaluation and Research
U.S. Food and Drug Administration
A postdoctoral fellowship is currently available in the Division of Therapeutic Proteins (DTP) within the Office of Biotechnology Products at the Center for Drug Evaluation and Research (CDER) of the U.S. Food and Drug Administration (FDA). The fellow will participate a research program to study the cell death mechanisms responsible for the action of a new class of protein therapeutics targeting the death receptors, including recombinant human TNF variants, TNF-related apoptosis ligand (TRAIL) and its receptor agonistic antibodies.
The selected participant will join a team of research focused on understanding the mechanisms of cancer drug action and resistance. Specific opportunities may include:
- Gaining knowledge in cancer cell biology, cancer cell biomarkers, and cancer drug resistance
- Learning the techniques for the assessment of product quality of therapeutic proteins for cancer treatment
The Research Participation Program for FDA is administered by the Oak Ridge Institute for Science and Education (ORISE). The initial appointment is for one year, but may be renewed upon recommendation of FDA contingent on the availability of funds. The participant will receive a monthly stipend depending on educational level and experience. The participant must show proof of health insurance. The appointment is full-time at the FDA in the Bethesda, Maryland, area. The laboratory is located on the main campus of National Institutes of Health (NIH) in Bethesda, MD, with access to its library, seminars, and core facilities. Participants do not become employees of FDA or the program administrator, and there are no fringe benefits paid.
- A Doctoral degree in biology or biochemistry with a strong background in molecular/cell biology received within the last five years.
- Experience with research on signal transduction pathways related to cell death is preferred.
How to Apply:
To be considered, please send a current CV/resume to the attention of FDArpp@orau.org. Please reference FDA-CDER-2014-0006 in all communications.
Current Research Opportunities
- Understanding the Influence of Water Technology Clusters and Cluster Organizations
- Sustainable Materials Research – Long-term Fate of Lead Enriched Waste Streams
- Transportation Greenhouse Gas Data and Public Information
- Economic Analysis in Support of Vehicle Greenhouse Gas Regulations
- Modeling and Analyzing Impacts of Particulate Matter on Convective Clouds