Research Project Description
Molecular Biology/Microbial Genomics Fellowship
Chronic Viral Diseases Branch
Division of High-Consequence Pathogens and Pathology
National Center for Emerging and Zoonotic Infectious Diseases
Centers for Disease Control and Prevention
A fellowship opportunity is currently available in the Chronic Viral Diseases Branch within the Division of High-Consequence Pathogens and Pathology (DHCPP) of the National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) at the Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia.
The selected participant will acquire, apply and refine molecular biology methods that include specimen processing, PCR techniques and various DNA sequencing methods for HPV detection and variant genotyping. S/he will analyze primary data with statistical methods and may process next-generation sequencing data. Further hands-on training will be provided for additional refined molecular methods to determine HPV copy numbers, methylation, cell enrichment and integration status, as they become applicable to the project. Specific activities may include:
- Determining HPV genotype variants via pyrosequencing and/or other sequencing methods.
- Performing sequence analysis, alignments and genotype assignments in accordance with nomenclature.
- Maintaining complete records of research proceedings to Laboratory Quality Assurance standards. Preparing technical reports and project summaries as requested.
- Conducting literature searches and reviewing ongoing developments in papillomavirus taxonomy and biology.
- Drafting manuscripts for peer review in scientific journals.
- Presenting research findings to scientific audiences.
- Performing quality control and safety procedures necessary for the performance of laboratory protocols involved in working with biohazard materials.
- Assisting in laboratory quality management activities as assigned.
- Participating in weekly meetings that address current scientific activities of the Branch.
This program, administered by ORAU through its contract with the U.S. Department of Energy to manage the Oak Ridge Institute for Science and Education, was established through an interagency agreement between DOE and CDC. The initial appointment is for one year, but may be renewed upon recommendation of CDC contingent on the availability of funds. The participant will received a monthly stipend commensurate with education level and experience. Proof of health insurance is required for participation in this program. The appointment is full-time at CDC in the Atlanta, Georgia, area. Participants do not become employees of CDC or the program administrator, and there are no fringe benefits paid.
- A Doctoral degree in molecular biology, molecular genetics, genomics or related field received within less than five years.
- Hands-on experience in advanced PCR techniques, DNA sequencing methods and assay development, and knowledge of next generation sequencing are a plus.
- Familiarity with analysis of sequencing data and statistics is desired.
How to Apply:
To be considered, please send a current CV/resume to the attention of CDCrpp@orau.org. Please reference CDC-NCEZID-2014-0060 in all communications.