Oak Ridge Sitewide Institutional Review Board
The Federal Policy for the Protection of Human Subjects, also known as the Common Rule, requires that each institution that engages in human subjects research establish an institutional review board (IRB). The IRB is to be composed of scientists, non-scientists and community members from differing backgrounds and perspectives.
The role of the IRB is to ensure that risks to human research subjects are minimized and reasonable relative to the anticipated benefits, and to protect the rights and welfare of research subjects in accordance with applicable federal regulations, state laws and U.S. Department of Energy (DOE) directives.
The Oak Ridge Institute for Science and Education (ORISE) has provided to the U.S. Department of Health and Human Services (HHS) written assurance that it will comply with the requirements of the Common Rule. Consistent with that commitment, ORISE administers the Oak Ridge Sitewide Institutional Review Board (ORSIRB) to conduct the reviews required for the approval of proposed or continuing studies involving human subjects.
By direction of the DOE Oak Ridge Office (ORO), the ORSIRB:
- Reviews proposed or continuing studies involving human participants conducted by employees or agents of ORISE, Oak Ridge National Laboratory, the Y-12 National Security Complex, East Tennessee Technology Park and other facilities as determined by DOE-ORO
- Serves as the site-specific IRB for research conducted by other entities sponsored by DOE or HHS involving current or former workers at the sites within DOE-ORO oversight