Beryllium-Associated Worker Registry Dashboards
Supplementary
Acronym List
| Acronym | Description |
|---|---|
| AMES | Ames Laboratory |
| AMWTP | Advanced Mixed Waste Treatment Project |
| ANL | Argonne National Laboratory |
| BAL | Bronchoalveolar Lavage |
| BAWR | Beryllium-Associated Worker Registry |
| Be | Beryllium |
| BeLPT | Beryllium Lymphocyte Proliferation Test |
| BeS | Beryllium Sensitization or Beryllium-Sensitized |
| BNL | Brookhaven National Laboratory |
| CBD | Chronic Beryllium Disease |
| CBDPP | Chronic Beryllium Disease Prevention Program |
| CFR | Code of Federal Regulations |
| CY | Calendar Year |
| DOD | U.S. Department of Defense |
| DOE | U.S. Department of Energy |
| DOE-ORO | U.S. Department of Energy - Oak Ridge Office |
| DOL | U.S. Department of Labor |
| EEOICPA | Energy Employees Occupational Illness Compensation Program Act |
| ETTP | East Tennessee Technology Park |
| EX | Arithmetic Mean |
| F | Percent Exceeding 0.2 µg/m3 |
| Fermi | Fermi National Accelerator Laboratory |
| HAN | Hanford Site |
| INL | Idaho National Laboratory |
| KAPL | Knolls Atomic Power Laboratory |
| LANL | Los Alamos National Laboratory |
| LBNL | Lawrence Berkeley National Laboratory |
| LLNL | Lawrence Livermore National Laboratory |
| LLNL BU | Lawrence Livermore National Laboratory Boston University (subcontractor) |
| LLNL CHES | Lawrence Livermore National Laboratory Clean Harbors Environmental Services (subcontractor) |
| LLNL ENVC | Lawrence Livermore National Laboratory Envirocon, Inc. (subcontractor) |
| NA | Not Applicable |
| NETL | National Energy Technology Laboratory |
| NNSA | DOE National Nuclear Security Administration |
| NNSS | Nevada National Security Site |
| NSC | National Security Campus |
| NSPS | National Strategic Protective Services, LLC for ETTP and ORNL |
| OIG | DOE Office of Inspector General |
| ORNL | Oak Ridge National Laboratory |
| ORISE | Oak Ridge Institute for Science and Education |
| OSHA | DOL Occupational Safety and Health Administration |
| PADUCAH | Paducah Site |
| PEL | Personal Exposure Limit |
| PNNL | Pacific Northwest National Laboratory |
| PTX | Pantex Plant |
| Respirator APF | Respirator Assigned Protection Factor |
| RF | Rocky Flats Closure Project |
| SLAC | SLAC National Accelerator Laboratory |
| SNL | Sandia National Laboratories |
| SOMD | Site Occupational Medical Director |
| SRS | Savannah River Site |
| SWPA | Southwestern Power Administration |
| TWA | Time Weighted Average |
| µg/m3 | Micrograms per Cubic Meter |
| UTL | Upper Tolerance Limit |
| WSI | Wackenhut Security Services, Inc. for ETTP, ORNL, and Y-12 |
| Y-12 | Y-12 National Security Complex |
| Y-12 ANS | Y-12 National Security Complex Atkins Nuclear Secured (subcontractor) |
| Y-12 NRE | Y-12 National Security Complex Navarro Research and Engineering (subcontractor) |
| Y-12 URS | Y-12 National Security Complex URS Corporation (subcontractor) |
Calculations
Beryllium Sensitization Algorithm (current until revisions to 10 CFR 850 are passed): An employee is considered sensitized if any one of the following clinical criteria and incidence rules for the case definition of beryllium sensitizations is met. Often, an employee’s data will satisfy multiple criteria, and their date of sensitization is calculated as the earliest date any one of these is met.
- 2 positive or abnormal BELPT results (based on 2 separate blood draws).
- 1 positive or abnormal plus 2 (or more) borderline BELPT results.
- A positive or abnormal bronchoalveolar lavage (BAL) result.
- A CBD evaluation with a finding of sensitization but no chronic beryllium disease (CBD).
Exposure Monitoring Statistics: These calculations are based on the methods described in the Statistical Methods and Software for the Analysis of Occupational Exposure Data with Non-Detectable Values. Due to the limitations in laboratory analytic methods approaching nano- scales much of the airborne exposure monitoring data are subject to left censoring with a measurement below the detectable limit. The methods applied estimate non-detectable levels using maximum likelihoods for randomly left censored, lognormal data with alternative non-parametric methods applied when the lognormal distribution is in doubt due to small sample sizes.
Pearson Product-Moment Correlation Coefficient: The Pearson Product-Moment Correlation Coefficient monitors the dose response represented by the BAWR data, and is calculated by site with the percent exceeding the action level and the percent beryllium sensitized or diagnosed with CBD.
References and Resources
American Journal of Industrial Medicine, Clinical and laboratory factors contributing to uninterpretable beryllium lymphocyte proliferation tests (BeLPT), Derek Smith, et. al., March 2018. Abstract: https://pubmed.ncbi.nlm.nih.gov/29574954
American Journal of Public Health, Illness Absences Among Beryllium Sensitized Workers, Janice Watkins, et. al., September 2014. Abstract: https://ajph.aphapublications.org/doi/abs/10.2105/AJPH.2014.302132
Beryllium-Associated Worker Registry 2017 Annual Report, Department of Energy, Office of the Associate Under Secretary for Environment, Health, Safety and Security. https://www.energy.gov/sites/prod/files/2019/05/f62/2017_Annual_BAWR_Report_Final.pdf
Chronic Beryllium Disease Prevention Program, 10 C.F.R. § 850 (1999). https://www.govinfo.gov/app/details/FR-1999-12-08/99-31181
Chronic Beryllium Disease Prevention Program, 10 C.F.R. § 850 (2012). https://www.govinfo.gov/app/details/CFR-2012-title10-vol4/CFR-2012-title10-vol4-part850
Department of Energy Technical Specification 1142, Beryllium Lymphocyte Proliferation Testing (BeLPT). DOE-SPEC-1142-2019. https://www.standards.doe.gov/standards-documents/1100/1142-dspec-2019
Department of Energy Technical Standard 1187, Beryllium-Associated Worker Registry Data Collection and Management Guidance. DOE-STD-1187-2019. https://www.standards.doe.gov/standards-documents/1100/1187-astd-2019
Department of Labor Occupational Safety and Health Administration, Beryllium - Overview. https://www.osha.gov/beryllium
Department of Labor Occupational Safety and Health Administration, OSHA’s Rulemaking to Protect Workers from Beryllium Exposure. https://www.osha.gov/beryllium/rulemaking
Notice of Proposed Rulemaking 10 CRR Part 850, Federal Register, June 2016. https://www.gpo.gov/fdsys/pkg/FR-2016-06-07/pdf/2016-12547.pdf
Notice of Proposed Rulemaking, Chronic Beryllium Disease Prevention Program, 10 CFR 850, page 36748. https://www.gpo.gov/fdsys/pkg/FR-2016-06-07/pdf/2016-12547.pdf
Occupational and Environmental Medicine, Exposure and genetics increase risk of beryllium sensitisation and chronic beryllium disease in the nuclear weapons industry, Michael Van Dyke, et. al., November 2011. Abstract: https://pubmed.ncbi.nlm.nih.gov/21460389
PEARSON function. https://support.microsoft.com/en-us/office/pearson-function-0c3e30fc-e5af-49c4-808a-3ef66e034c18
STAND: Statistical Analysis of Non-Detects. https://cran.r-project.org/web/packages/STAND/index.html
Statistical Methods and Software for the Analysis of Occupational Exposure Data with Non-Detectable Values, Frome EL and Wambach PF, ORNL/TM-2005/52. https://www.csm.ornl.gov/esh/aoed/ORNLTM2005-52.pdf
The R Project for Statistical Computing. https://www.r-project.org
Worker Safety and Health Program, 10 C.F.R. § 851.10 (2006). https://www.govinfo.gov/app/details/CFR-2020-title10-vol4/CFR-2020-title10-vol4-sec851-10