January 21, 2021
Radiation Emergency Assistance Center/Training Site Cytogenetic Biodosimetry Laboratory Director Adayabalam Balajee, Ph.D., co-authored a manuscript recently published in Nature Communications. The manuscript, titled “Radiation-induced DNA damage and repair effects on 3D genome organization,” describes how the authors used genetic, molecular and computational approaches to explore how the human 3D genome responds to ionizing radiation exposure.
Human DNA, the blueprint of life, is organized in a three dimensional structure in a cell’s nucleus and this approach could be helpful for investigating the role of 3D genome organization in various sporadic and hereditary human diseases. This research project between ORAU and the University of Tennessee, Knoxville, resulted from an ORAU Directed Research and Development grant. Read the manuscript to learn more.
ORISE Featurecast: Catching up with Adayabalam Balajee
Adayabalam Balajee, Ph.D., director of the Radiation Emergency Assistance Center/Training Site Cytogenetic Biodosimetry Laboratory, is a busy and prolific researcher. Most recently, he co-authored a manuscript in partnership with colleagues at the University of Tennessee that was recently published in Nature Communications. He has also developed the Chromosome Challenge, which gamifies the identification of dicentric chromosomes with the ultimate goal of recruiting people to assist with the identification process in the event of a radiation emergency. Not unexpectedly, he has other projects in the pipeline.
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