Providing expertise to answer questions regarding the medical management of radiation incidents worldwide
Through the management of the Radiation Emergency Assistance Center/Training Site (REAC/TS), the Oak Ridge Institute for Science and Education (ORISE) enables the U.S. Department of Energy to respond efficiently to medical emergencies involving radiological/nuclear materials by providing expert advice and consultation.
REAC/TS prepares providers for radiological/nuclear emergencies through didactic and hands-on education. REAC/TS also provides medical advice, specialized continuing education courses and the unique capability of on-site assistance for the treatment of radiation exposure.
Treatment of combined injuries during a radiation incident
When a radiation incident victim suffers not only radiation exposure but other significant injuries, REAC/TS can help responders with the proper treatment protocol. Serious medical problems always have priority over radiological concerns, and immediate attention is directed to life-threatening problems.
REAC/TS has developed protocols for medical management and radiation monitoring to highlight priorities in the medical cases of radiation victims. To help first responders and physicians, REAC/TS has designed a treatment algorithm for medical management and monitoring to highlight priorities in the care of radiation victims.
Radiation medication countermeasures
REAC/TS professionals maintain a registry of clinical information and provide expertise to practitioners worldwide on the use of calcium-diethylenetriaminepentaacetic acid (DTPA) and zinc-diethylenetriaminepentaacetic acid (DTPA) and Radiogardase Prussian Blue (Radiogardase™).
Calcium-DTPA and zinc-DTPA are injectable chelating agents used to enhance the excretion of plutonium and other transuranics from the body. Radiogardase Prussian Blue (Radiogardase™) binds to radiocesium and thallium and enhances their excretion from the body.
Radiation Accident Registry
REAC/TS staff maintains the Radiation Accident Registry with important information concerning radiological/nuclear incidents worldwide. REAC/TS also maintains a DTPA and Prussian Blue registry as well as a tissue repository.
Information for these accident registries is gathered from many sources, including the World Health Organization, International Atomic Energy Agency, U.S. Nuclear Regulatory Commission, state radiological health departments, as well as medical and health physics literature. The registries also include information from medical professionals who call REAC/TS for assistance when an incident occurs.
Registries maintained by REAC/TS include:
- U.S. and Foreign Radiation Accident Registry
- Diethylenetriaminepentaacetic Acid (DTPA) User Registry
- Prussian Blue Registry
Data from the registry system are used to determine the efficacy of treatment protocols, to monitor trends in morbidity and mortality and as a database for follow-up of accident survivors.