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Cytogenetic Biodosimetry Laboratory Video

Cytogenetic biodosimetry is the most accurate method, or the “gold standard,” for determining the amount of radiation dose absorbed by a patient’s body. Using certain white blood cells, special techniques are used to identify chromosome abnormalities, which indicate damage in the most critical area for radiation injury—the cell’s genetic material in DNA, which make up the chromosomes. The results of such analyses are essential for guiding medical management of patients exposed to radiation that could result from a radiation incident.

The Oak Ridge Institute for Science and Education (ORISE) has played a major role in dose assessment and the medical management of persons affected by accidental exposures to ionizing radiation. Through Radiation Emergency Assistance Center/Training Site’s (REAC/TS) 24-hour emergency response program at ORISE, the center has provided training, consulting and/or assistance in the response to a variety of radiation accidents or incidents since its formation in 1976.

To learn more about the ORISE Cytogenetic Biodosimetry Laboratory (CBL), view our video that details the step-by-step cytogenetic biodosimetry process.