Acronym List

Acronym Description
AMES Ames Laboratory
AMWTP Advanced Mixed Waste Treatment Project
ANL Argonne National Laboratory
BAL Bronchoalveolar Lavage
BAWR Beryllium-Associated Worker Registry
Be Beryllium
BeLPT Beryllium Lymphocyte Proliferation Test
BeS Beryllium Sensitization or Beryllium-Sensitized
BNL Brookhaven National Laboratory
CBD Chronic Beryllium Disease
CBDPP Chronic Beryllium Disease Prevention Program
CERCLA Comprehensive Environmental Response, Compensation, and Liability Act of 1980
CFR Code of Federal Regulations
CY Calendar Year
DOD U.S. Department of Defense
DOE U.S. Department of Energy
DOE-ORO U.S. Department of Energy - Oak Ridge Office
DOL U.S. Department of Labor
EEOICPA Energy Employees Occupational Illness Compensation Program Act
EHSS Office of the Associate Under Secretary for Environment, Health, Safety and Security
EHSS-10 Office of Health and Safety
ETTP East Tennessee Technology Park
EX Arithmetic Mean
F Percent Exceeding 0.2 µg/m3
Fermi Fermi National Accelerator Laboratory
HAN Hanford Site
INL Idaho National Laboratory
KAPL Knolls Atomic Power Laboratory
KCP Kansas City Plant
LANL Los Alamos National Laboratory
LBNL Lawrence Berkeley National Laboratory
LLNL Lawrence Livermore National Laboratory
LLNL BU Lawrence Livermore National Laboratory Boston University (subcontractor) 
LLNL CHES Lawrence Livermore National Laboratory Clean Harbors Environmental Services (subcontractor) 
LLNL ENVC Lawrence Livermore National Laboratory Envirocon, Inc. (subcontractor)
LLNL NW Lawrence Livermore National Laboratory North Wind Services, LLC (subcontractor)
NA Not Applicable
NETL National Energy Technology Laboratory
NNSA DOE National Nuclear Security Administration
NNSS Nevada National Security Site
NSC National Security Campus
NSPS National Strategic Protective Services, LLC for ETTP and ORNL
NTS Nevada Test Site
OIG DOE Office of Inspector General
ORNL Oak Ridge National Laboratory
ORISE Oak Ridge Institute for Science and Education
OSHA DOL Occupational Safety and Health Administration
PADUCAH Paducah Site
PEL Personal Exposure Limit
PII Personally Identifiable Information
PNNL Pacific Northwest National Laboratory
PRS Paducah Remediation Services
PTX Pantex Plant
RCRA Resource Conservation and Recovery Act of 1976
Respirator APF Respirator Assigned Protection Factor
RF Rocky Flats Closure Project
SLAC SLAC National Accelerator Laboratory
SNL Sandia National Laboratories
SOMD Site Occupational Medical Director
SRS Savannah River Site
SWPA Southwestern Power Administration
TWA Time Weighted Average
µg/m3 Micrograms per Cubic Meter
UTL Upper Tolerance Limit
WSHP Worker Safety and Health Program
WSI Wackenhut Security Services, Inc. for ETTP, ORNL, and Y-12
Y-12 Y-12 National Security Complex
Y-12 ANS Y-12 National Security Complex Atkins Nuclear Secured (subcontractor)
Y-12 NRE Y-12 National Security Complex Navarro Research and Engineering (subcontractor) 
Y-12 URS Y-12 National Security Complex URS Corporation (subcontractor)


Beryllium Sensitization Algorithm (current until revisions to 10 CFR 850 are passed): A worker is considered sensitized if any one of the following clinical criteria and incidence rules for the case definition of beryllium sensitizations is met. Often, a worker’s data will satisfy multiple criteria, and their date of sensitization is calculated as the earliest date any one of these is met.

  • 2 positive or abnormal beryllium proliferation test (BELPT )results (based on 2 separate blood draws).
  • 1 positive or abnormal plus 2 (or more) borderline BELPT results.
  • A positive or abnormal bronchoalveolar lavage (BAL) result.
  • A CBD evaluation with a finding of sensitization but no chronic beryllium disease (CBD).

Exposure Monitoring Statistics: These calculations are based on the methods described in the Statistical Methods and Software for the Analysis of Occupational Exposure Data with Non-Detectable Values. Due to the limitations in laboratory analytic methods approaching nano- scales much of the airborne exposure monitoring data are subject to left censoring with a measurement below the detectable limit. The methods applied estimate non-detectable levels using maximum likelihoods for randomly left censored, lognormal data with alternative non-parametric methods applied when the lognormal distribution is in doubt due to small sample sizes.

Pearson Product-Moment Correlation Coefficient: The Pearson Product-Moment Correlation Coefficient monitors the dose response represented by the Beryllium-Associated Worker Registry (BAWR) data, and is calculated by site with the percent exceeding the action level and the percent beryllium sensitized or diagnosed with CBD.

References and Resources

Chronic Beryllium Disease Prevention Program, 10 CFR § 850 (1999).

Chronic Beryllium Disease Prevention Program, 10 CFR § 850 (2012).

Proposed Changes to Chronic Beryllium Disease Prevention Program, 10 CFR Part 850 (2016).

Department of Energy, Office of Environment, Health, Safety and Security. (2019). DOE-SPEC-1142-2019, Beryllium Lymphocyte Proliferation Testing (BeLPT). Washington, DC: Department of Energy. Retrieved from

Department of Energy, Office of Environment, Health, Safety and Security. (2019). DOE-STD-1187-2019, Beryllium-Associated Worker Registry Data Collection and Management Guidance. Washington, DC: Department of Energy. Retrieved from

Department of Energy, Office of the Associate Under Secretary for Environment, Health, Safety and Security. (2017). Beryllium-Associated Worker Registry 2017 Annual Report. Retrieved from

Department of Labor, Occupational Safety and Health Administration. (n.d.). Overview. Retrieved from Beryllium:

Frome, E.L., Frome, D.P. (2015). STAND: Statistical Analysis of Non-Detects. R package version 4.0.

Frome, E.L., & Wambach, P.F. (2005). Statistical Methods and Software for the Analysis of Occupational Exposure Data with Non-Detectable Values. ORNL/TM-2005/52.

Occupational Exposure to Beryllium and Beryllium Compounds in Construction and Shipyard Sectors, 29 CFR Parts 1915 and 1926 (2020).

PEARSON function. Microsoft Excel.

R Core Team. (2023). R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria.

Smith, D. E., Golden, A. P., Stange, A. W., Barker, E., Mroz, M., Barón, A. E., Ghosh, D., Maier, L., Cragle, D., & Newman, L. S. (2018). Clinical and laboratory factors contributing to uninterpretable beryllium lymphocyte proliferation tests (BeLPT). American Journal of Industrial Medicine61(7), 592–604.

Van Dyke, M. V., Martyny, J. W., Mroz, M. M., Silveira, L. J., Strand, M., Cragle, D. L., Tankersley, W. G., Wells, S. M., Newman, L. S., & Maier, L. A. (2011). Exposure and genetics increase risk of beryllium sensitisation and chronic beryllium disease in the nuclear weapons industry. Occupational and Environmental Medicine68(11), 842–848.

Watkins, J. P., Ellis, E. D., Girardi, D. J., Cragle, D. L., & Richter, B. S. (2014). Illness absences among beryllium sensitized workers. American Journal of Public Health104(11), e165–e169.

Worker Safety and Health Program, 10 CFR § 851.10 (2006).