Beryllium-Associated Worker Registry Dashboards
Supplementary
Acronym List
| Acronym | Description |
|---|---|
| AMES | Ames Laboratory |
| AMWTP | Advanced Mixed Waste Treatment Project |
| ANL | Argonne National Laboratory |
| BAL | Bronchoalveolar Lavage |
| BAWR | Beryllium-Associated Worker Registry |
| Be | Beryllium |
| BeLPT | Beryllium Lymphocyte Proliferation Test |
| BeS | Beryllium Sensitization or Beryllium-Sensitized |
| BNL | Brookhaven National Laboratory |
| CBD | Chronic Beryllium Disease |
| CBDPP | Chronic Beryllium Disease Prevention Program |
| CERCLA | Comprehensive Environmental Response, Compensation, and Liability Act of 1980 |
| CFR | Code of Federal Regulations |
| CY | Calendar Year |
| DOD | U.S. Department of Defense |
| DOE | U.S. Department of Energy |
| DOE-ORO | U.S. Department of Energy - Oak Ridge Office |
| DOL | U.S. Department of Labor |
| EEOICPA | Energy Employees Occupational Illness Compensation Program Act |
| EHSS | Office of the Associate Under Secretary for Environment, Health, Safety and Security |
| EHSS-10 | Office of Health and Safety |
| ETTP | East Tennessee Technology Park |
| EX | Arithmetic Mean |
| F | Percent Exceeding 0.2 µg/m3 |
| Fermi | Fermi National Accelerator Laboratory |
| GSVCS | Golden SVCS, LLC |
| HAN | Hanford Site |
| INL | Idaho National Laboratory |
| KAPL | Knolls Atomic Power Laboratory |
| KCNSC | Kansas City National Security Campus |
| LANL | Los Alamos National Laboratory |
| LANL N3B | Newport News Nuclear BWXT Los Alamos |
| LBNL | Lawrence Berkeley National Laboratory |
| LLNL | Lawrence Livermore National Laboratory |
| LLNL BU | Lawrence Livermore National Laboratory Boston University (subcontractor) |
| LLNL CHES | Lawrence Livermore National Laboratory Clean Harbors Environmental Services (subcontractor) |
| LLNL ENVC | Lawrence Livermore National Laboratory Envirocon, Inc. (subcontractor) |
| LLNL NW | Lawrence Livermore National Laboratory North Wind Services, LLC (subcontractor) |
| NA | Not Applicable |
| NETL | National Energy Technology Laboratory |
| NNSA | DOE National Nuclear Security Administration |
| NNSS | Nevada National Security Site |
| NSC | National Security Campus |
| NSPS | National Strategic Protective Services, LLC for ETTP and ORNL |
| NTS | Nevada Test Site |
| OIG | DOE Office of Inspector General |
| ORNL | Oak Ridge National Laboratory |
| ORISE | Oak Ridge Institute for Science and Education |
| OSHA | DOL Occupational Safety and Health Administration |
| PADUCAH | Paducah Site |
| PEL | Personal Exposure Limit |
| PII | Personally Identifiable Information |
| PNNL | Pacific Northwest National Laboratory |
| PRS | Paducah Remediation Services |
| PTX | Pantex Plant |
| RCRA | Resource Conservation and Recovery Act of 1976 |
| Respirator APF | Respirator Assigned Protection Factor |
| RF | Rocky Flats Closure Project |
| SLAC | SLAC National Accelerator Laboratory |
| SNL | Sandia National Laboratories |
| SOMD | Site Occupational Medical Director |
| SRS | Savannah River Site |
| SWPA | Southwestern Power Administration |
| TWA | Time Weighted Average |
| µg/m3 | Micrograms per Cubic Meter |
| UTL | Upper Tolerance Limit |
| WSHP | Worker Safety and Health Program |
| WSI | Wackenhut Security Services, Inc. for ETTP, ORNL, and Y-12 |
| Y-12 | Y-12 National Security Complex |
| Y-12 ANS | Y-12 National Security Complex Atkins Nuclear Secured (subcontractor) |
| Y-12 NRE | Y-12 National Security Complex Navarro Research and Engineering (subcontractor) |
| Y-12 URS | Y-12 National Security Complex URS Corporation (subcontractor) |
Calculations
Beryllium Sensitization Algorithm (current until revisions to 10 CFR 850 are passed): A worker is considered sensitized if any one of the following clinical criteria and incidence rules for the case definition of beryllium sensitizations is met. Often, a worker’s data will satisfy multiple criteria, and their date of sensitization is calculated as the earliest date any one of these is met.
- 2 positive or abnormal beryllium proliferation test (BeLPT) results (based on 2 separate blood draws).
- 1 positive or abnormal plus 2 (or more) borderline BeLPT results.
- A positive or abnormal bronchoalveolar lavage (BAL) result.
- CBD evaluation with a finding of sensitization but no chronic beryllium disease (CBD).
Exposure Monitoring Statistics: These calculations are based on the methods described in the Statistical Methods and Software for the Analysis of Occupational Exposure Data with Non-Detectable Values. Due to the limitations in laboratory analytic methods approaching nano- scales much of the airborne exposure monitoring data are subject to left censoring with a measurement below the detectable limit. The methods applied estimate non-detectable levels using maximum likelihoods for randomly left censored, lognormal data with alternative non-parametric methods applied when the lognormal distribution is in doubt due to small sample sizes.
Pearson Product-Moment Correlation Coefficient: The Pearson Product-Moment Correlation Coefficient monitors the dose response represented by the Beryllium-Associated Worker Registry (BAWR) data, and is calculated by site with the percent exceeding the action level and the percent beryllium sensitized or diagnosed with CBD.
References and Resources
Chronic Beryllium Disease Prevention Program, 10 CFR § 850 (1999). https://www.govinfo.gov/app/details/FR-1999-12-08/99-31181
Chronic Beryllium Disease Prevention Program, 10 CFR § 850 (2012). https://www.govinfo.gov/app/details/CFR-2012-title10-vol4/CFR-2012-title10-vol4-part850
Proposed Changes to Chronic Beryllium Disease Prevention Program, 10 CFR Part 850 (2016). https://www.gpo.gov/fdsys/pkg/FR-2016-06-07/pdf/2016-12547.pdf
Department of Energy, Office of Environment, Health, Safety and Security. (2019). DOE-SPEC-1142-2019, Beryllium Lymphocyte Proliferation Testing (BeLPT). Washington, DC: Department of Energy. Retrieved from https://www.standards.doe.gov/standards-documents/1100/1142-dspec-2019
Department of Energy, Office of Environment, Health, Safety and Security. (2019). DOE-STD-1187-2019, Beryllium-Associated Worker Registry Data Collection and Management Guidance. Washington, DC: Department of Energy. Retrieved from https://www.standards.doe.gov/standards-documents/1100/1187-astd-2019
Department of Energy, Office of the Associate Under Secretary for Environment, Health, Safety and Security. (2017). Beryllium-Associated Worker Registry 2017 Annual Report. Retrieved from https://www.energy.gov/sites/prod/files/2019/05/f62/2017_Annual_BAWR_Report_Final.pdf
Department of Labor, Occupational Safety and Health Administration. (n.d.). Overview. Retrieved from Beryllium: https://www.osha.gov/beryllium
Frome, E.L., Frome, D.P. (2015). STAND: Statistical Analysis of Non-Detects. R package version 4.0. https://CRAN.R-project.org/package=STAND
Frome, E.L., & Wambach, P.F. (2005). Statistical Methods and Software for the Analysis of Occupational Exposure Data with Non-Detectable Values. ORNL/TM-2005/52. https://info.ornl.gov/sites/publications/Files/Pub57493.pdf
Occupational Exposure to Beryllium and Beryllium Compounds in Construction and Shipyard Sectors, 29 CFR Parts 1915 and 1926 (2020). https://www.govinfo.gov/content/pkg/FR-2020-08-31/pdf/2020-18017.pdf
PEARSON function. Microsoft Excel. https://support.microsoft.com/en-us/office/pearson-function-0c3e30fc-e5af-49c4-808a-3ef66e034c18
R Core Team. (2023). R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria. https://www.R-project.org/
Smith, D. E., Golden, A. P., Stange, A. W., Barker, E., Mroz, M., Barón, A. E., Ghosh, D., Maier, L., Cragle, D., & Newman, L. S. (2018). Clinical and laboratory factors contributing to uninterpretable beryllium lymphocyte proliferation tests (BeLPT). American Journal of Industrial Medicine, 61(7), 592–604. https://doi.org/10.1002/ajim.22842
Van Dyke, M. V., Martyny, J. W., Mroz, M. M., Silveira, L. J., Strand, M., Cragle, D. L., Tankersley, W. G., Wells, S. M., Newman, L. S., & Maier, L. A. (2011). Exposure and genetics increase risk of beryllium sensitisation and chronic beryllium disease in the nuclear weapons industry. Occupational and Environmental Medicine, 68(11), 842–848.https://doi.org/10.1136/oem.2010.064220
Watkins, J. P., Ellis, E. D., Girardi, D. J., Cragle, D. L., & Richter, B. S. (2014). Illness absences among beryllium sensitized workers. American Journal of Public Health, 104(11), e165–e169. https://doi.org/10.2105/AJPH.2014.302132
Worker Safety and Health Program, 10 CFR § 851.10 (2006). https://www.govinfo.gov/app/details/CFR-2020-title10-vol4/CFR-2020-title10-vol4-sec851-10