Protecting the rights and welfare of human research subjects
The U.S. Department of Energy (DOE) is committed to the protection of human research participants in all research funded by DOE, conducted at DOE institutions, or performed by DOE employees or their contractors. The Oak Ridge Institute for Science and Education (ORISE) works closely with DOE to support its mission and ensure effective implementation of the DOE Human Subjects Protection Program.
Through technical assistance support, ORISE helps DOE execute and maintain strategic initiatives that uphold the highest standards and regulations for the protection of human subjects.
Key areas of focus include:
Education and resources
Find useful education resources and tools for IRB chairs, administrators, researchers and program managers, provided by the DOE Human Subjects Protection Program.
Regulations and requirements
Learn more about policy and requirements documents, including ethical principles, federal regulations, DOE special requirements, and HIPAA regulations, that DOE follows in its implementation of the DOE Humans Subjects Protection Program.
Institutional Review Boards
- Central DOE IRB (CDOEIRB)
Established in January 2010, the CDOEIRB serves as DOE’s IRB of record for study protocols that involve employees of DOE or its contractors.
- Central DOE IRB-Classified (CDOEIRB-C)
The CDOEIRB-C (established in 2012) serves as DOE's IRB of record for DOE sites that do not have a classified IRB but have study protocols that involve classified (in part or totality) human subjects research. It also serves as DOE's IRB of record for all classified and unclassified intelligence-related human subjects research funded through the Strategic Intelligence Partnership Program.
- Oak Ridge Sitewide IRB (ORSIRB)
ORISE manages the ORSIRB, which addresses human subjects protection issues for research involving workers or researchers at DOE facilities in Oak Ridge, Tenn. This standard operating procedure outlines the purpose, scope and operations of the IRB to assure research meets ethical principles and complies with federal regulations that pertain to human subject protection.