Latest Episode
The struggle is worth it: A conversation with Kalidas Mainali, Ph.D., ORISE postdoctoral fellow at the USDA ARS
Kalidas Mainali, Ph.D., is an ORISE postdoctoral fellow at the U.S. Department of Agriculture Agricultural Research Service. He is stationed at the USDA ARS Eastern Regional Research Center in Wyndmoor, Pennsylvania, where Mainali is studying methods for creating biofuels and other valuable resources from agricultural waste. Mainali is a native of Nepal who also studied in Scotland, so he brings a wealth of world-wise experience to his research, but says that he ultimately decided to pursue his Ph.D. in the United States because of the extensive research opportunities available here. In this conversation, Mainali talks about his educational journey, his relationships with his mentors, and his plans for the future.
Previous Episodes
Jin Whan Bae is a Nuclear Reactor Analyst in the Research and Test Reactor Physics Group within the Nuclear Energy and Fuel Cycle Division at Oak Ridge National Laboratory in Oak Ridge, Tennessee. He was the recipient of an ORISE Mentor Award in 2024. In this episode of the ORISE Featurecast, Bae talks to host Michael Holtz about his research experience, which covers a wide range of topics related to nuclear science, including fuel cycle modeling and analysis, fission and fusion reactor physics analysis and reactor design, and machine learning applications for nuclear engineering. The conversation focuses on Bae’s educational trajectory, how he has served as a mentor and been mentored by others, and the life shift involved in moving from Korea to the United States. On the personal side, Bae shares his vision for nuclear energy as a force for prosperity without the cost of fossil fuels and carbon emissions.
The 2025-26 cohort of Albert Einstein Distinguished Educator Fellows has begun their fellowship year in Washington, D.C. Natajsa Brown, an educator from Ocean Springs, Miss., is serving as co-host for this cohort's series of ORISE Featurecasts. In this conversation with host Michael Holtz, Brown introduces herself and what led her to apply for the AEF. As you'll hear, it's going to be a great season of conversations. Welcome, Natasja!
Peer review is evaluation of an individual or groups' work by another individual or group with expertise in the same field or a related field. Peer-reviewed work may include proposals to conduct scientific research, ongoing research, or a submitted papers based on ongoing or completed research. In this episode of the ORISE Featurecast, host Michael Holtz talks to Colleen Iversen, Ph.D., a former ORISE research participation program participant who now serves as a peer reviewer for ORISE. Their conversation covers the importance of the peer review process to the advancement of science, the newly developed ORISE Peer Review Resource Hub, the need for young investigators to become peer reviewers, and how peer review makes you a better scientist and proposal writer.
Janine Pino, data librarian for Oak Ridge National Laboratory's Research Library and Information Services, discussed “AI Literacy: Secure and Effective Use of Generative AI” as part of the ORISE Symposium on Thursday, Aug. 28, 2025. In this episode of the ORISE Featurecast, Pino takes a deeper dive into the topic of generative AI, including how to craft strong prompts, critically evaluate AI-generated output, and navigate the opportunities and pitfalls of using these tools in scholarly research and writing.
As a member of the Research Library team, Pino specializes in bibliometric tools, data analysis, and technical training. She joined the lab in 2022 after serving as an academic librarian, online learning liaison, and graduate program instructor. Pino completed her master's degree in information sciences at the University of Tennessee. She welcomes questions and collaborative efforts to improve lab-wide preservation and sharing of scientific and technical information.
Valisha Edwards is an ORISE Fellow in the FBI Visiting Scientist Program. At the time of this conversation, Edwards was in the Counterterrorism and Forensic Science Research Unit where she managed multiple projects ranging from primary explosives to toxicology, overseeing analytical techniques and instrumentation that pertains to these projects. "I typically map out the research in general in its entirety, and then I just do the testing that's required for each project," she said. Edwards has previous experience as a forensic chemist and a police laboratory criminalist. Still, like many of us, she struggles with imposter syndrome. Learn more about Edwards and her research during this thoughtful and engaging conversation.
Jake Janssen is an ORISE Research Program Participant appointed to the U.S. Army Medical Research Institute of Chemical Defense. His research focuses on neuroscience, and hazardous chemicals in trauma medicine. In this episode of the ORISE Featurecast, he says "We look at novel polytrauma scenarios involving organophosphates and other pharmaceutical grade drugs, and traumatic brain injuries or TBIs. We want to improve upon treatment guidelines and combat casualty care through new polypharmacy methods, and also identify and study chemicals of concern so that the United States is more prepared for an impending chemical threat from any adversary we may see." In Janssen's conversation with host Michael Holtz, he talks about the underlying importance of his research, his career trajectory and some of the obstacles he has overcome in his life and career.
Vivian Egan is a self-described nerd who did math for fun as a kid. As a former ORISE research program participant at the Air Force Research Laboratory, Egan is doing time series studies on human behavior, two concepts that don't ordinarily intersect. Time series studies usually focus on financial or environmental data, so focusing on human behavior is novel. She's studying how people multitask and their reaction time to certain stimuli (think loud noises or other interruptions). In a recent conversation with the ORISE Featurecast, Egan talked in-depth about her research, the trajectory of her career, obstacles she's faced and successes she's realized along the way. Learn more about ORISE research opportunities at AFRL and other U.S. Department of Defense programs.
Jingfan Chen, Ph.D., says she understood that her research had impact outside the laboratory setting when she was studying the solubility of cancer drugs. Lack of solubility -- put simply, whether a drug molecule can dissolve in liquid -- keeps potential cancer drugs from reaching the market. Her study of ways to make these drugs more soluble opened her eyes to the importance of her research outside the lab. Chen took first place in the 2024 ORISE Postdoc Poster Session Showcase for her research on the quality and safety of compounded off-brand semaglutide-based medications. As the demand for weight-loss drugs like Ozempic and Wegovy has grown, there have been occasional shortages of the name-brand medications. Off-brand compounded medications are more affordable than their name brand counterparts, but can often contain ingredients that are non FDA approved. In this episode of the ORISE Featurecast Chen talks about her work on the poster that took the award, other research she has done, her career trajectory and so much more.
ORISE Featurecast host Michael Holtz is the first to admit he isn't a fan of math. What he knows now is that he wasn't encouraged or given the ability to grow into his understanding of mathematics. In this episode, he and Zachary Minchow-Proffitt, a 2025 Albert Einstein Distinguished Educator Fellow, have a conversation about social emotional learning with Ralph Pantozzi, also a current AEF Fellow, and Dr. Sharon Sikora, an AEF alumnus. Social emotional learning helps educators understand how to encourage their students by meeting them where ever they may be emotionally when they come into the classroom, taking comparison bias out of the process, and helping students understand that they don't have to grasp a difficult concept immediately; it takes time. This was a meaningful and wide-ranging conversation.
Rebecca Masline, Ph.D., is a researcher at the Plasma Science and Fusion Center at the Massachusetts Institute of Technology. She completed her Ph.D. at University of California San Diego in 2023. She took third place in the ORISE Postdoc Poster Session Showcase in 2024 for her poster on helium ash in the exhaust streams created by nuclear fusion. In this conversation, Masline explains that when atoms combine to make fusion happen, we get energy, which we like, but we also get one ash of helium as a byproduct. Masline’s research focuses on characterizing and understanding the behavior of helium in the exhaust stream of these nuclear fusion devices and investigates whether we can use that to characterize efficiency of a fusion power plant as a whole. She also talks about her mentors and what drives her as a scientist. Read more about Masline and her research.
